Download and read online The Clinical Nanomedicine Handbook in PDF and EPUB Designed to foster a stronger awareness and exploration of the subject by practicing clinicians, medical researchers and scientists, The Clinical Nanomedicine Handbook discusses the integration of nanotechnology, biology, and medicine from a clinical point of view. The book highlights relevant research and applications by specialty; it examines nanotechnology in depth, and the potential to solve medical problems. It also increases literacy in nanotechnology, and allows for more effective communication and collaboration between disciplines. Details worldwide developments in nanomedicine Provides a comprehensive roadmap of the state of nanomedicine in numerous medical specialties Bridges the gap between basic science research, engineering, nanotechnology, and medicine This text discusses what nanomedicine is, how it is currently used, and considers its potential for future applications. It serves as a reference for clinicians, including physicians, nurses, health-care providers, dentists, scientists, and researchers involved in clinical applications of nanotechnology.
Download and read online Handbook of Clinical Nanomedicine in PDF and EPUB This handbook (55 chapters) provides a comprehensive roadmap of basic research in nanomedicine as well as clinical applications. However, unlike other texts in nanomedicine, it not only highlights current advances in diagnostics and therapeutics but also explores related issues like nomenclature, historical developments, regulatory aspects, nanosimilars and 3D nanofabrication. While bridging the gap between basic biomedical research, engineering, medicine and law, the handbook provides a thorough understanding of nano’s potential to address (i) medical problems from both the patient and health provider's perspective, and (ii) current applications and their potential in a healthcare setting.
Download and read online The Handbook of Nanomedicine in PDF and EPUB Nanomedicine is defined as the application of nanobiotechnology in clinical medicine, which is currently being used to research the pathomechanism of disease, refine molecular diagnostics, and aid in the discovery, development, and delivery of drugs. In The Handbook of Nanomedicine, Third Edition, Prof. Kewal K. Jain updates, reorganizes, and replaces information in the comprehensive second edition in order to capture the most recent advances in this dynamic field. Important components of nanomedicine such as drug delivery via nanobiotechnology and nanopharmaceuticals as well as nanooncology, where the greatest number of advances are occurring, are covered extensively. As this text is aimed at nonmedical scientists, pharmaceutical personnel, as well as physicians, descriptions of the technology involved and other medical terminology are kept as clear and simple as possible. In depth and cutting-edge, The Handbook of Nanomedicine, Third Edition informs its readers of the ever-growing field of nanomedicine, destined to play a significant role in the future of healthcare.
Download and read online Handbook of Clinical Nanomedicine Two Volume Set in PDF and EPUB The enormous advances in nanomedicine in the past decade have necessitated a growing need for an authoritative and comprehensive reference source that can be relied upon by scientists, clinicians, students, and industry and policy makers alike. The Handbook of Clinical Nanomedicine: From Bench to Bedside is designed to offer a global perspective on the wonders of nanomedicine. The handbook aims to provide a broad survey of various interconnected topics pertaining to nanomedicine. It is intended to be a stand-alone, easily accessible volume that examines the entire "product wheel" from creation of nanomedical products to final market introduction, all accomplished in a user-friendly format. Specifically, everything from bio-nanomaterials and nanodevices from the R&D stage to patent protection, clinical regulatory aspects, and eventual commercialization is encompassed in this book. In addition to highlighting cutting-edge technologies, the book addresses critical topics such as ethics, safety and toxicity, environmental health, nanoeconomics, business strategy, licensing, intellectual property, FDA law, EPA law, and governmental policy issues. With contributions from international experts, the diverse team of editors has compiled a book that provides a unified perspective to these varied topics. While many books focus on nanomedicine, nanotechnology, or nanoscience, none provide the medical applications of nanotechnology with both a clinical and business angle. Furthermore, most of the currently available books on the market fail to highlight the truly global nature of nanomedicine.
Download and read online Handbook of Clinical Nanomedicine in PDF and EPUB The exciting advances in nanomedicine in the past two decades highlight the growing need for an authoritative and comprehensive reference that can be relied upon by scientists, clinicians, academics, industry, students, lawyers, and policy-makers alike. With this in mind, the Handbook of Clinical Nanomedicine: Law, Business, Regulation, Safety, and Risk and its related companion volumes in the series aim to provide a broad survey of interconnected topics pertaining to clinical nanomedicine. This is the second volume in the series. Each volume is intended to be a stand‐alone reference source, presented in a user-friendly format for easy access. This volume examines nanomedical products’ entire "product life cycle" from the creation of nanomedical products to the final market introduction. It not only provides a comprehensive roadmap of basic and clinical research but also tackles critical topics such as regulatory science, intellectual property law, risk analysis, toxicology, nano-characterization, and commercialization activities. All chapters contain keywords, figures in full color, author biographies, and an extensive list of references. The handbook is truly essential reading for the novice and the expert alike in fields such as medicine, law, biotechnology, pharmaceutical sciences, engineering, policy, future studies, ethics, licensing, and toxicology, among others. While bridging the gap between basic biomedical research, engineering, medicine, law, and commercialization, the handbook allows readers to gain a thorough understanding of nano’s potential to address medical problems from both the patient and the health provider’s point of view; current applications and potential in a healthcare setting; regulatory, environment, and health issues; and intellectual property, licensing, and commercialization issues as well as business considerations. The editor and assistant editors have skillfully curated each chapter to reflect the most relevant and current information possible. The range of topics covered as well as the diverse selection of distinguished authors is truly impressive. The multidisciplinary approach of this handbook as well as its focus on not only scientific and technical aspects of nanomedicine but also legal, regulatory, policy, and commercial aspects will attract a global audience. In short, the Handbook of Clinical Nanomedicine: Law, Business, Regulation, Safety, and Risk promises to be a standard reference for any serious practitioner in this expansive field.
Download and read online Handbook of Nanobiomedical Research in PDF and EPUB This book consists of 4 volumes containing about 70 chapters covering all the major aspects of the growing area of nanomedicine. Leading scientists from 15 countries cover all major areas of nanobiomedical research — materials for nanomedicine, application of nanomedicine in therapy of various diseases, use of nanomedicines for diagnostic purposes, technology of nanomedicines, and new trends in nanobiomedical research. This is the first detailed handbook specifically addressing various aspects of nanobiomedicine. Readers are treated to cutting-edge research and the newest data from leading researchers in this area. Contents:Materials for Nanomedicine:Liposomal Nanomedicines (Amr S Abu Lila, Tatsuhiro Ishida and Theresa M Allen)Solid Lipid Nanoparticles for Biomedical Applications (Karsten Mäder)Micellar Nanopreparations for Medicine (Rupa Sawant and Aditi Jhaveri)Nanoemulsions in Medicine (William B Tucker and Sandro Mecozzi)Drug Nanocrystals and Nanosuspensions in Medicine (Leena Peltonen, Jouni Hirvonen and Timo Laaksonen)Polymeric Nanosystems for Integrated Image-Guided Cancer Therapy (Amit Singh, Arun K Iyer and Mansoor M Amiji)Polysaccharide-Based Nanocarriers for Drug Delivery (Carmen Teijeiro, Adam McGlone, Noemi Csaba, Marcos Garcia-Fuentes and María J Alonso)Dendrimers for Biomedical Applications (Lisa M Kaminskas, Victoria M McLeod, Seth A Jones, Ben J Boyd and Christopher J H Porter)Layer-by-Layer Nanopreparations for Medicine — Smart Polyelectrolyte Multilayer Capsules and Coatings (Rawil F Fakhrullin, Gleb B Sukhorukov and Yuri M Lvov)Inorganic Nanopreparations for Nanomedicine (James Ramos and Kaushal Rege)Silica-Based Nanoparticles for Biomedical Imaging and Drug Delivery Applications (Stephanie A Kramer and Wenbin Lin)Carbon Nanotubes in Biomedical Applications (Krunal K Mehta, Elena E Paskaleva, Jonathan S Dordick and Ravi S Kane)Core-Shell Nanoparticles for Biomedical Applications (Mahmoud Elsabahy and Karen L Wooley)Structure–Activity Relationships for Tumor-Targeting Gold Nanoparticles (Erik C Dreaden, Ivan H El-Sayed and Mostafa A El-Sayed)Silver Nanoparticles as Novel Antibacterial and Antiviral Agents (Stefania Galdiero, Annarita Falanga, Marco Cantisani, Avinash Ingle, Massimiliano Galdiero and Mahendra Rai)Magnetic Nanoparticles for Drug Delivery (Rainer Tietze, Harald Unterweger and Christoph Alexiou)Quantum Dots as a Platform Nanomaterial for Biomedical Applications (Eleonora Petryayeva, Roza Bidshahri, Kate Liu, Charles A Haynes, Igor L Medintz, and W Russ Algar)Applications in Therapy:The Application of Nanomedicine to Cardiovascular Diseases (Kevin M Bardon, Olivier Kister and Jason R McCarthy)Nanomedicines for Restenosis Therapy (J E Tengood, I Fishbein, R J Levy and M Chorny)Nanopreparations for Cancer Treatment and Diagnostics (Jayant Khandare, Shashwat Banerjee and Tamara Minko)Nanoparticles in the Gastrointestinal Tract (Abraham Rubinstein)Nanopreparations for Oral Administration (D Hubbard, D J Brayden and H Ghandehari)Nanopreparations for Central Nervous System Diseases (Leyuan Xu and Hu Yang)Nanoparticles for Dermal and Transdermal Delivery: Permeation Pathways and Applications (Marianna Foldvari, Marjan Gharagozloo and Christine Li)Lysosomes and Nanotherapeutics: Diseases, Treatments, and Side Effects (Rachel L Manthe and Silvia Muro)Nanostructured Biomaterials for Inhibiting Cancer Cell Functions (Lijuan Zhang and Thomas J Webster)Nanomedicine in Otorhinolaryngology (Carl Philpott)Nanomedicines for Ocular Administration (Yolanda Diebold)Nano-antibiotics: Nanotechnology in Fighting Against Infectious Diseases (Jessica Kemp, Julius Edson, Young Jik Kwon)Nanoparticles as Adjuvants for Vaccination (Juan M Irache, Ana I Camacho and Carlos Gamazo)Nanopreparations for Gene Delivery (Viola B Morris and Vinod Labhasetwar)Cancer Hyperthermia Using Nanomagnetic Particles and Induction of Immune Responses (Takeshi Kobayashi)Clinical Experience with Liposomal Doxorubicin (Giuseppe Visani and Alessandro Isidori)Clinical Experience with Nanoparticle Albumin Bound (Nab) Paclitaxel (Abraxane®) (Prakash Vishnu and Vivek Roy)Applications in Diagnostics:Nano Advantages in Diagnostic Imaging (William T Phillips and Beth Goins)Superparamagnetic Iron Oxides as Imaging Probes of Metastases and Vulnerable Atherosclerotic Plaques (Mary L Mazzanti and Alexei A Bogdanov, Jr)Nanoparticulate Contrast Agents for CT, SPECT and PET Imaging (Suna Erdogan and Mine Silindir)Nanotargeted Radiopharmaceuticals for Nuclear Imaging and Radiotherapy (Gann Ting, Yun-Long Tseng, Chih-Hsien Chang and Te-Wei Lee)Nanoengineering at the Gas–Liquid Interface: Gas-Filled Microbubbles as Tools for Molecular Imaging and Drug Delivery (Alexander L Klibanov)Nanotechnology for Multimodality Imaging: Applications in Disease Detection and Treatment Guidance (Jinzi Zheng, Raquel De Souza David Jaffray and Christine Allen)Theranostic Nanopreparations for Medicine (Anthony J McGoron)Fluorescent Silica Nanoparticles for Medical Imaging (Jeremy Tharkur, Maria Alejandra Ricaurte and Swadeshmukul Santra)Engineered Gold Nanoparticles as Contrast Agents for Biological Medical Imaging (Anna M Sitarski, Sanjeev Kandpal, Jeremy Grant, Andrew Doolittle, Matthew Newsom and Michael D Mason)Photoluminescent Nanoparticles for Optical Imaging in Biology and Medicine (María Teresa Fernández-Argüelles, Rosario Pereiro, José M Costa-Fernández and Alfredo Sanz-Medel)Metal Particles for Photoacoustic Imaging (Dipanjan Pan)Nanoelectrodes for Biomedical Applications (Haibin Shi and Joanne I Yeh)Nanosensors for Biomedicine (Mary K Balaconis and Heather A Clark)In Vivo Photoacoustic Detection of Circulating Cells and Nanoparticles (Jin-Woo Kim, Ekaterina I Galanzha and Vladimir P Zharov)Raman Micro-Spectroscopy as a Non-Invasive Tool to Follow the Intracellular Fate of Nanoparticles (Tatyana Chernenko, Max Diem and Vladimir Torchilin)Clinical Experience with Nanoparticles in Imaging (Patrick D Sutphin and Mukesh Harisinghani)Biology, Safety and Novel Concepts in Nanomedicine:Biology and Safety:Biological Requirement and Safety Assessment of Nanomedicines (Banu Zolnik, Simona Bancos, Jae Seung Kim and Nakissa Sadrieh)Anatomical and Physicochemical Factors Controlling Nanoparticle Pharmacokinetics (S M Moghimi and Z S Farhangrazi)Immunological Issues with Nanomedicines: Immunogenicity, Hypersensitivity, Accelerated Clearance and Immune Suppression (Janos Szebeni and Wim Jiskoot)Toxicology of Mesoporous Silica Particles and Their Uses in Nanomedicine (Xin Xia, Natalia Kupferschmidt and Alfonso E Garcia-Bennett)Cellular Responses Induced by Nanoparticles (Masanori Horie)Regulatory Aspects of Pharmaceutical Nanopreparations (Gerard M Jensen and Linda Soo Hoo)A Short Course on the Chemistry Manufacturing and Control of Liposome-based Pharmaceutical Products (Simon Eastman and Tom Redelmeier)Preclinical to Clinical Development of Nanomedicines (Sonke Svenson)Novel Concepts in Nanomedicine:Organelle-Targeted Nanocarriers (Alexander Koshkaryev)Bacteriophage-Targeted Nanomedicine and Molecular Imaging (Tao Wang and Radhika Narayanaswamy)Stimuli-Sensitive Nanostructured Systems for Biomedical Applications (Barbara Blanco-Fernandez, Angel Concheiro and Carmen Alvarez-Lorenzo)Biomedical Nanopreparations with Controlled Geometry (Catherine A Fromen, Stuart S Dunn and Joseph M DeSimone)Biomimetic Systems in Nanomedicine (Ana Maria Carmona-Ribeiro)Nanoreactors for Biomedical Applications (Fabian Itel, Ionel Adrian Dinu, Pascal Tanner, Ozana Fischer and Cornelia G Palivan)"Click" Reactions: An Emerging Tool for Biology (Annie Castonguay and Dusica Maysinger) Readership: Academics, researchers, graduate students and professionals interested in contemporary nanomedicine. Keywords:Nanomedicine;Drug Delivery Systems;Materials for Nanomedicine;Nanomedicine in Therapy;Nanomedicine in Diagnostics;NanoparticlesKey Features:Covers the whole field of nanobiomedicineIncludes chapters from many leading world renowned scientistsProvides cutting-edge data
Download and read online Handbook of Personalized Medicine in PDF and EPUB This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical setting that creates the fertile ground for the practical utility of personalized medicine decisions and also enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational nanomedicine and informatics, stem cell therapy approaches, modeling and predictability of drug response, pharmacogenetics-guided drug prescription, pediatric drug dosing, pharmacovigilance and regulatory aspects, ethical and cost-effectiveness issues, pharmacogenomics knowledge bases, personal genome sequencing, molecular diagnostics, as well as information-based medicine.
Download and read online Polymer Nanoparticles for Nanomedicines in PDF and EPUB This volume serves as a valuable handbook for the development of nanomedicines made of polymer nanoparticles because it provides researchers, students, and entrepreneurs with all the material necessary to begin their own projects in this field. Readers will find protocols to prepare polymer nanoparticles using different methods, since these are based on the variety of experiences that experts encounter in the field. In addition, complex topics such as, the optimal characterization of polymer nanoparticles is discussed, as well as practical guidelines on how to formulate polymer nanoparticles into nanomedicines, and how to modify the properties of nanoparticles to give them the different functionalities required to become an efficient nanomedicine for different clinical applications. The book also discusses the translation of technology from research to practice, considering aspects related to industrialization of preparation and aspects of regulatory and clinical development.
Download and read online Handbook of Materials for Nanomedicine in PDF and EPUB The fast developing field of nanomedicine uses a broad variety of materials to serve as delivery systems for drugs, genes, and diagnostic agents. This book is the first attempt to put under one cover all major available information about these materials, both still on experimental levels and already applied in patients.
Download and read online Handbook of Immunological Properties of Engineered Nanomaterials in PDF and EPUB The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.
Download and read online Handbook of the Philosophy of Medicine in PDF and EPUB This is the first wide-ranging, multi-authored handbook in the field of philosophy of medicine, covering the underlying conceptual issues of many important social, political and ethical issues in health care. It introduces and develops over 70 topics, concepts, and issues in the field. It is written by distinguished specialists from multiple disciplines, including philosophy, health sciences, nursing, sociology, political theory, and medicine. Many difficult social and ethical issues in health care are based on conceptual problems, most prominently on the definitions of health and disease, or on epistemological issues regarding causality or diagnosis. Philosophy is the discipline that deals with such conceptual, metaphysical, epistemological, methodological, and axiological matters. This handbook covers all the central concepts in medicine, such as ageing, death, disease, mental disorder, and well-being. It is an invaluable source for laypeople, academics with an interest in medicine, and health care specialists who want be informed and up to date with the relevant discussions. The text also advances these debates and will set the agenda for years to come.
Download and read online Understanding Nanomedicine in PDF and EPUB This book comprehensively covers a broad range of therapeutic and diagnostic applications of nanotechnology, providing descriptions of cutting-edge discoveries along with historical perspectives. The text focuses on nanomaterials and nanoparticles, the sectors that hold the most promise for the future of medicine. The author look at how nanotechnology can impact cancer treatment, clinical neuroscience, tissue engineering, drug delivery, and diagnostics. He also discusses the worldwide governmental regulatory impact on nanomedicine.
Download and read online Handbook of Low level Laser Therapy in PDF and EPUB This book compiles cutting-edge contributions from the world's leading experts in Photobiomodulation and LLLT. Chapters cover general concepts, mechanisms of action, in vitro studies, pre-clinical animal studies, veterinary applications and a wide range of clinical topics. Edited by Michael Hamblin from Massachusetts General Hospital and Harvard Medical School, aided by two prominent researchers (Marcelo Sousa and Tanupriya Agrawal), this book will appeal to anyone involved in the basic science, translational aspects and clinical applications of LLLT
Download and read online Handbook of Harnessing Biomaterials in Nanomedicine in PDF and EPUB This book concentrates on the use of biomaterials in nanomedicine. The areas of focus include drug delivery by polymers, lipids, and carbohydrates for the delivery of small molecules, RNA interference, and proteins; the use of nano-proteins such as antibodies and peptides as targeting agents for therapeutics and diagnosis; the use of nanocarrier-based biomaterials for manipulation of stem cells; different aspects of toxicity of nanocarriers (the immune response, liver toxicity, and many more); and success stories of biomaterials that have reached the clinics. The book covers theoretical and experimental analysis of various biomaterials that are used in nanomedicine, research methods and preparation techniques, and several promising applications.
Download and read online Handbook of Nanophysics in PDF and EPUB The tools of nanodiagnostics, nanotherapy, and nanorobotics are expected to revolutionize the future of medicine, leading to presymptomatic diagnosis of disease, highly effective targeted treatment therapy, and minimum side effects. Handbook of Nanophysics: Nanomedicine and Nanorobotics presents an up-to-date overview of the application of nanotechnology to molecular and biological processes, medical imaging, targeted drug delivery, and cancer treatment. Each peer-reviewed chapter contains a broad-based introduction and enhances understanding of the state-of-the-art scientific content through fundamental equations and illustrations, some in color. This volume shows how the materials, tools, and techniques of nanotechnology, such as enzymatic nanolithography, biomimetic approaches, and force spectroscopy, are currently used in biological applications, including living cell biochips, biosensors, protein recognition, and the analysis of biomolecules. Drawing on emerging toxicology research, it examines the impact and risks of nanomaterials on human health and the environment. Researchers at the forefront of the field cover tissue engineering, diagnostic, drug delivery, and therapeutic applications, including organs derived from nanomaterials, quantum dots and magnetic nanoparticles for imaging, pharmaceutical nanocarriers, targeted magnetic particles and biodegradable nanoparticles for drug delivery, and cancer treatment using gold nanoparticles. They also explain how cells and skin respond to these nanomaterials. In addition, the book investigates the next generation of nanotechnology research that is focused on nanorobotics and its potential in detecting and destroying cancer cells and detecting and measuring toxic chemicals. It considers the roles nanoheaters, nanomotors, and nanobatteries can play in this new technology. Nanophysics brings together multiple disciplines to determine the structural, electronic, optical, and thermal behavior of nanomaterials; electrical and thermal conductivity; the forces between nanoscale objects; and the transition between classical and quantum behavior. Facilitating communication across many disciplines, this landmark publication encourages scientists with disparate interests to collaborate on interdisciplinary projects and incorporate the theory and methodology of other areas into their work.